Publications

A systems approach to infectious disease

Eckhardt M, Hultquist JF, Kaake RM, Hüttenhain R, Krogan NJ.

Nat Rev Genet. 2020 Jun;21(6):339-354. doi: 10.1038/s41576-020-0212-5. Epub 2020 Feb 14.

Viral Fitness Landscapes in Diverse Host Species Reveal Multiple Evolutionary Lines for the NS1 Gene of Influenza A Viruses

Muñoz-Moreno R, Martínez-Romero C, Blanco-Melo D, Forst CV, Nachbagauer R, Benitez AA, Mena I, Aslam S, Balasubramaniam V, Lee I, Panis M, Ayllón J, Sachs D, Park MS, Krammer F, tenOever BR, García-Sastre A.

Cell Rep. 2019 Dec 17;29(12):3997-4009.e5. doi: 10.1016/j.celrep.2019.11.070.

The ETS transcription factor ELF1 regulates a broadly antiviral program distinct from the type I interferon response

Seifert LL, Si C, Saha D, Sadic M, de Vries M, Ballentine S, Briley A, Wang G, Valero-Jimenez AM, Mohamed A, Schaefer U, Moulton HM, García-Sastre A, Tripathi S, Rosenberg BR, Dittmann M.

PLoS Pathog. 2019 Nov 4;15(11):e1007634. doi: 10.1371/journal.ppat.1007634. eCollection 2019 Nov.

Identification and dynamic quantification of regulatory elements using total RNA

Duttke SH, Chang MW, Heinz S, Benner C.

Genome Res. 2019 Nov;29(11):1836-1846. doi: 10.1101/gr.253492.119. Epub 2019 Oct 24.

An Influenza Virus Entry Inhibitor Targets Class II PI3 Kinase and Synergizes with Oseltamivir

O'Hanlon R, Leyva-Grado VH, Sourisseau M, Evans MJ, Shaw ML.

ACS Infect Dis. 2019 Oct 11;5(10):1779-1793. doi: 10.1021/acsinfecdis.9b00230. Epub 2019 Sep 9.

Structural basis for influenza virus NS1 protein block of mRNA nuclear export

Zhang K, Xie Y, Muñoz-Moreno R, Wang J, Zhang L, Esparza M, García-Sastre A, Fontoura BMA, Ren Y.

Nat Microbiol. 2019 Oct;4(10):1671-1679. doi: 10.1038/s41564-019-0482-x. Epub 2019 Jul 1.

Metascape provides a biologist-oriented resource for the analysis of systems-level datasets

Zhou Y, Zhou B, Pache L, Chang M, Khodabakhshi AH, Tanaseichuk O, Benner C, Chanda SK.

Nat Commun. 2019 Apr 3;10(1):1523. doi: 10.1038/s41467-019-09234-6.

Editorial overview: Emerging viruses: interspecies transmission: Expect the unexpected

García-Sastre A, Richt JA.

Curr Opin Virol. 2019 Feb;34:iii-vi. doi: 10.1016/j.coviro.2019.02.003. Epub 2019 Mar 21.

Directed Non-targeted Mass Spectrometry and Chemical Networking for Discovery of Eicosanoids and Related Oxylipins

Watrous JD, Niiranen TJ, Lagerborg KA, Henglin M, Xu YJ, Rong J, Sharma S, Vasan RS, Larson MG, Armando A, Mora S, Quehenberger O, Dennis EA, Cheng S, Jain M.

Cell Chem Biol. 2019 Mar 21;26(3):433-442.e4. doi: 10.1016/j.chembiol.2018.11.015. Epub 2019 Jan 17.

Nucleolar Relocalization of RBM14 by Influenza A Virus NS1 Protein

Beyleveld G, Chin DJ, Moreno Del Olmo E, Carter J, Najera I, Cillóniz C, Shaw ML.

mSphere. 2018 Nov 14;3(6):e00549-18. doi: 10.1128/mSphereDirect.00549-18.

Live imaging of airway epithelium reveals that mucociliary clearance modulates SARS-CoV-2 spread

Becker ME, Martin-Sancho L, Simons LM, McRaven MD, Chanda SK, Hultquist JF, Hope TJ.

Nat Commun. 2024 Nov 2;15(1):9480. doi: 10.1038/s41467-024-53791-4.

Outcome of SARS-CoV-2 reinfection depends on genetic background in female mice

Singh G, García-Bernalt Diego J, Warang P, Park SC, Chang LA, Noureddine M, Laghlali G, Bykov Y, Prellberg M, Yan V, Singh S, Pache L, Cuadrado-Castano S, Webb B, García-Sastre A, Schotsaert M.

Nat Commun. 2024 Nov 23;15(1):10178. doi: 10.1038/s41467-024-54334-7.